When a new list is available, it will be announced in the ITIS newsletter, and you can import and process the list using the 'Retrieve Opiates list' function.
After performing this function, all substances in your administration will be examined for the existence of the chemical on the list. When you indicate that a substance is on the opiate list, the process will respect that even when the substance is not on the opiates list.
If you want to follow the list completely, check the 'Respect list' box. While processing, the opiate indication will be removed from substances that are not on the list and added to compounds that are on the list.